If there is no stunt and/or blitz, the EDGE rusher usually goes on feel. If you get a tackle with happy feet, you bull rush him and put him on skates. If you get a QB like Fields, scheme rushes are best to keep containment up the middle and outside.
There are so many factors and I'm only speaking D1 level in college. I didn't play in college, but my best friend was a D1 EDGE and played in Europe until he was 35. Each level is a huge elevation in complexity.